Meerkat

"Meerkat" is a computational tool to identify genomic rearrangements from high-throughput sequencing data. It uses multiple clusters of discordant reads to identify more complex rearrangements than available methods and uses split-reads to ensure high accuracy, followed by analysis of sequence homology at the breakpoints. The mechanisms forming these rearrangements can be inferred based on the features of breakpoints. Click here to download and here to learn more about Meerkat.